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Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: Three new products generated in the mithramycin producer streptomyces argillaceus through combinatorial biosynthesis

机译：Mithramycin SK，一种具有改善的治疗指数的新型抗肿瘤药，Mithramycin SA和脱myososyl-mithramycin SK：通过组合的生物合成，在光神霉素生产商argillaceus中产生了三种新产品

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Remsing, Lily; González, A.M.; Nur-e-Alam, M.; Fernández-Lozano, M.J.; Fernández Braña, Alfredo Javier; Rix, U.; Oliveira, M.A.; Méndez Fernández, María del Carmen; Salas Fernández, José Antonio; Rohr, J.;
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年度 2003
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1. Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin [J] . Ernestina Fernández, Ulrike Wei?bach, César Sánchez Reillo, Journal of bacteriology . 1998,第18期

机译：从抗生药合成霉素的过程中，从链霉菌编码糖基转移酶的两个基因的糖基转移酶的二糖的转移的鉴定。
2. Ketopremithramycins and Ketomithramycins,Four New Aureolic Acid-Type Compounds Obtained upon Inactivation of Two Genes Involved in the Biosynthesis of the Deoxysugar Moieties of the Antitumor Drug Mithramycin by Streptomyces argillaceus,Reveal Novel [J] . Sanjay Gayakwad, Bruce B.Jarvis Chemtracts . 2003,第11期

机译：ketopremithramycins和ketomithramycins，四个新的金黄色酸型化合物的失活，涉及两个基因的灭活，这两个基因涉及链霉菌链霉菌抗肿瘤药物光神霉素的脱氧糖部分的生物合成。
3. Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin. [J] . F Lombó, K Siems, A F Bra?a, Journal of bacteriology . 1997,第10期

机译：精链链霉菌基因的克隆和插入失活涉及抗肿瘤聚酮化合物光神霉素的糖部分的生物合成的最早步骤。
4. Investigation of the Mechanism of Action for Mithramycin and the Biosynthesis of L-Rednose in Saquayamycins [D] . Weidenbach, Stevi. 2017

机译：沙霉素中光神霉素的作用机理和L-红糖的生物合成研究
5. Mithramycin SK A Novel Antitumor Drug with Improved Therapeutic Index Mithramycin SA and Demycarosyl-mithramycin SK: Three New Products Generated in the Mithramycin Producer Streptomyces argillaceus through Combinatorial Biosynthesis [O] . Lily L. Remsing, Ana M. González, Mohammad Nur-e-Alam, -1

机译：Mithramycin SK（具有改善的治疗指数的新型抗肿瘤药）Mithramycin SA和Demycarosyl-mithramycin SK：通过组合生物合成在光神霉素生产者链霉菌中产生了三种新产品。
6. Ketopremithramycins and Ketomithramycins, Four New Aureolic Acid-Type Compounds Obtained upon Inactivation of Two Genes Involved in the Biosynthesis of the Deoxysugar Moieties of the Antitumor Drug Mithramycin by Streptomyces Argillaceus, Reveal Novel Insights into Post-PKS Tailoring Steps of the Mithramycin Biosynthetic Pathway [O] . Lily L. Remsing, Jose Garcia-Bernardo, Ana Gonzalez, 2002

机译：Ketoperemithramycins和Ketomithramycins，通过链霉菌氨基霉素灭火的两种基因灭活的四种新的野鸭酸型化合物，揭示了在Mithramycin生物合成途径的PKS剪裁步骤中的新颖见解

Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: Three new products generated in the mithramycin producer streptomyces argillaceus through combinatorial biosynthesis

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